Wednesday, June 30, 2010

Oxygen Concentrators Prove Effective For Treating Hypoxemic Children In Developing Countries

June 5th 2010 Posted at early symptoms mesothelioma
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Several university studies have determined that using oxygen concentrators are a valuable tool for treating children with hypoxemia in developing countries. The World Health Organization (WHO) also recommends supplying oxygen to children in developing with oxygen concentrators. The WHO prefers oxygen concentrators to compressed oxygen cylinders because cylinders pose significant cost and logistic problems.

Hypoxemia is a common complication of acute lower respiratory tract infections in children. The disease is an abnormal deficiency in the concentration of oxygen in arterial blood. When people think of health problems for children in developing countries, they rarely think about respiratory illness. Pneumonia alone contributes to between 750,000 and 1.2 million neonatal deaths and an undetermined number of stillbirths each year worldwide. The majority of deaths from pneumonia occur in developing countries, where facilities for early detection are few and far between. Finding oxygen therapy equipment is a challenge throughout the third world.

For children with hypoxemia in developing countries, early detection and treatment is the key to survival. Here are some of the most common warning signs associated with hypoxemia:

* Rapid breathing (more than 60 breaths per minute)

* Nasal flaring

* Grunting

* Head nodding

* General depression

* Lethargy

The combination of several of these physical signs can be used to predict hypoxemia in children with acute respiratory infection (ARI) with reasonable accuracy. Healthcare workers and parents can be taught these warning s signs to help aid in early diagnosis.

Unfortunately, oxygen therapy is not part of the first line of treatment for most children with ARI in developing countries. Oxygen in these poor countries tends to be given to already seriously ill children, often with poor results. Oxygen can be much more useful if given at earlier stages of respiratory disease. Studies indicate that oxygen concentrators may improve management of childhood asthma in developing countries and are more cost-effective than conventional compressed oxygen cylinders. The only requirement for oxygen concentrators is a reliable source of electricity. Even this can be overcome with a small generator or a portable oxygen concentrator with re-chargeable batteries.

Oxygen concentrators are currently being successfully used in district hospitals in Egypt, Mongolia, Papua New Guinea and Malawi. Research by the WHO has determined that one oxygen concentrator can provide low flow oxygen to up to 4 children. The organization also believes that savings offered by oxygen concentrators could be used to purchase other essential medicines and supplies. Charity organizations would be wise to purchase oxygen concentrators for children in developing countries. Oxygen concentrators provide life saving oxygen while offering exceptional value.

About the Author – Chuck Jaymes is an indoor air quality professional for Oxygen Concentrators and offers reviews and information about Portable Oxygen Concentrator for OscarAir, Inc.

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Saturday, June 26, 2010

New Virus Held Responsible For Respiratory Infection In Children

A new virus, named human bocavirus, that may be responsible for causing severe respiratory infections in children has been identified by a group of Swedish researchers.]]>

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Friday, June 25, 2010

Second Hand Exposure To Smoke In Childhood Can Cause Respiratory Problems Later

Researchers from National Institute of Environmental Health Sciences (NIEHS) had found that second-hand exposure to smoke during childhood increases the ]]>

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Thursday, June 24, 2010

Cannabis to be tested to help patients with respiratory diseases

"All substances are poisonous, there is none which is not a poison; the right dose differentiates a poison from a remedy" Paracelsus, circa 1538Breathlessness ]]>

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Wednesday, June 23, 2010

Targeted Radiation for Early Breast Cancer a Good Option: Study

•Certain Smokers More Apt to Quit Over Price Hikes•Newer Drugs Beat Gleevec in Head-to-Head Trials•Researchers Report Treatment Headway Against Lung Cancer•Novel Drug Combats Advanced MelanomaMore...

SATURDAY, June 5 (HealthDay News) -- Radiation therapy that targets a specific area of the breast is as effective as whole-breast radiation in reducing breast cancer recurrence in some women and is far more convenient, a new study suggests.

Researchers led by Jayant S. Vaidya of University College London, and David Joseph of the University of Western Australia, examined the medical records of almost 1,000 breast cancer patients who received (targeted) intraoperative radiotherapy and a nearly equal number who underwent whole-breast external beam radiation.

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Drug Combination Offers Hope in Asthma, Chronic Bronchitis Treatment

A study conducted by researchers at Washington University has highlighted a new combination drug treatment for asthma and chronic bronchitis. The new ]]>

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Tuesday, June 22, 2010

New Technique to Identify Respiratory Problems in Children

The Great Ormond Street Hospital doctors have developed a novel method to identify chronic lung problems in children under the age of five. The test is ]]>

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Monday, June 21, 2010

Respiratory Problems In 9/11 Rescuers

Research has shown that rescue workers of New York City's fire department involved in 9/11 rescue efforts have been found to have reduced lung functions ]]>

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Saturday, June 19, 2010

Infants in damp housing at risk of developing wheeze

01 Feb 10

By Yvette Martyn

Damp housing is the strongest risk factor for the development of severe wheeze in the first year of life, according to a Dutch study.

The study - published this month in Pediatric Pulmonology - examined the prevalence and risk factors for wheeze in 1,115 infants through a detailed questionnaire.

Infants living in damp housing were 2.5 times more likely to wheeze, making it the main modifiable risk factor.

The study, which is published in the latest issue of Paediatric Pulmonology, found that a history of eczema, having a sibling with asthma and visiting day care were associated with the development of wheeze, recurrent wheeze and severe wheeze.

But the researchers found no relationship between wheeze and maternal smoking and suggested that this may be because mothers who smoke through pregnancy are less likely to have a family history of asthma.

Study author Dr Paul Brand, consultant paediatrician at the Princess Amalia Children's Clinic of the Isala Klinieken Hospital in Zwolle, the Netherlands said: ‘Damp housing, although uncommon, is a strong risk factor for troublesome wheeze in infants. Studies are needed to examine the effect of reducing home dampness on the severity of wheeze in young children.’

Pediatr Pulmonol 2010;45:149-156

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Friday, June 18, 2010

The Excisional Biopsy



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Thursday, June 17, 2010

Wednesday, June 16, 2010

Tuesday, June 15, 2010

Air Pollution Exposure Increases Risk Of Heart And Respiratory Disease

Exposure to fine particulate air pollution could be responsible for increase in cardiac and lung-related hospital admissions, reports a latest study published in the recent issue of JAMA.]]>

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Monday, June 14, 2010

A Balanced Diet can Keep Asthma, Wheezing at Bay in Teens

Teens, especially those who smoke, may be at an increased risk of respiratory symptoms such as asthma it they forego a healthy and balanced diet. The ]]>

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Sunday, June 13, 2010

Apples During Pregnancy Help Lower Asthma, Wheezing Risk in Kids

Eating an apple a day during pregnancy will not only kept the doctor away for expecting mums, but it can also help lower the risk of their kids developing asthma and wheezing.]]>

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Saturday, June 12, 2010

Genes too Play Vital Role in Boosting Chronic Bronchitis Risk

It is long known that smoking is responsible for respiratory diseases like chronic bronchitis. However, Swedish researchers have discovered that genes ]]>

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Friday, June 11, 2010

Babies With Asthmatic Mums Have an Increased Risk of Wheezing

Kids with mums who have allergies or asthma have an increased risk of wheezing in the chest if they take part in baby swimming before 6 months of age, according to a new study.]]>

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Thursday, June 10, 2010

Intense Exercise Can Produce Wheezing Even In Healthy Children

Heavy exercise can provoke the onset of temporary lung problems and other symptoms typically associated with asthma in children who are not actually asthmatic, ]]>

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•Targeted Radiation for Early Breast Cancer a Good Option: Study•Newer Drugs Beat Gleevec in Head-to-Head Trials•Researchers Report Treatment Headway Against Lung Cancer•Novel Drug Combats Advanced MelanomaMore...
SUNDAY, June 6 (HealthDay News) -- Boosting cigarette taxes can cause smoking rates to plummet among people struggling with alcohol, drug and/or mental disorders, new research suggests.
The study authors found that raising the price of cigarettes by just 10 percent translates into more than an 18 percent drop in smoking among such individuals.
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Wednesday, June 9, 2010

Pill Shrinks Some Lung Cancers

Crizotinib Shows Promise for Lung Cancer Patients With ALK Genetic Abnormality By Charlene Laino
WebMD Health News Reviewed by Laura J. Martin, MD

June 7, 2010 (Chicago) -- An experimental pill shrank tumors in lung cancer patients who have a specific genetic abnormality.

After treatment with the drug crizotinib, tumors shrank or stopped growing in more than 90% of 82 advanced lung cancer patients with the genetic abnormality. In 57%, tumors shrank by 30% or more. Side effects were generally mild.

"That's huge for a population of lung cancer patients where most treatments have only a 10% response (tumor shrinkage) rate, with considerable toxicity," says Indiana University's George W. Sledge Jr., MD, incoming president of American Society of Clinical Oncology (ASCO).

It’s too early to know if the drug actually extends lives. And only the 4% of lung cancer patients worldwide with the gene abnormality targeted by the drug are typically helped by crizotinib.

Still, that translates to more than 8,000 people in the U.S. each year, Sledge tells WebMD.

The findings were presented at ASCO's annual meeting.

Assess Your Risk for  the 5 Most Common Cancers

How Crizotinib Works in Lung Cancer

Crizotinib blocks an aberrant protein called ALK that is critical for the growth and survival of cancer cells.

In some people, an aberration causes the ALK gene to fuse with another gene, typically EML4 in lung cancer.

This, in turn, inappropriately turns on the ALK gene so it produces more and more of the ALK protein, driving tumor growth.

No one knows exactly why it happens, but lung cancer patients with the abnormality are generally nonsmokers. And they're typically younger, in their 50s on average. The abnormality is not inherited.

It's easy to test for ALK aberration, "so we can tell right away if you’re likely to respond to the drug," says Roy Herbst, MD, chief of thoracic medical oncology at the University of Texas M.D. Anderson Cancer Center in Houston. He was not involved with the work.

Only 28% Chance of Lung Cancer Progression

People in the study had advanced non-small-cell lung cancer (NSCLC), the most common type of cancer. In many cases, the disease had already spread to other parts other body. They had failed to respond to an average of three, and up to seven, drugs.

Most were former light smokers or never-smokers, and all had the ALKgene fusion.

After an average of six months of treatment, there was only a 28% chance that the cancer got worse, and responses to crizotinib have lasted for up to 15 months, says one of the study's leaders, Yung-Jue Bang, MD, of the Seoul National University College of Medicine in South Korea.

About 50% of patients on crizotinib had mild diarrhea or nausea that generally occurred early on and resolved after a few weeks. Ten percent had elevated liver enzymes that sometimes required stopping treatment, usually temporarily.

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OSU Asthma Expert: If Mom Is Not Breathing, Neither Is Baby

A common breathing problem is also one of the most serious chronic medical conditions complicating pregnancy. According to recent research and despite specific guidelines and recommendations advocating for aggressive asthma management, healthcare providers treat asthma attacks in pregnant women differently than in non-pregnant women.

Researchers at The Ohio State University Medical Center sought to determine if pregnant women who come to the emergency department with acute asthma symptoms receive the same anti-inflammatory medicines and steroids to treat flare-ups as non-pregnant women.


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Tuesday, June 8, 2010

•Targeted Radiation for Early Breast Cancer a Good Option: Study•Certain Smokers More Apt to Quit Over Price Hikes•Newer Drugs Beat Gleevec in Head-to-Head Trials•Researchers Report Treatment Headway Against Lung CancerMore...
SATURDAY, June 5 (HealthDay News) -- Taking the popular mineral supplement selenium doesn't reduce the likelihood of lung cancer recurrence, a new study reveals.
Lead author Dr. Daniel D. Karp, a professor in the department of thoracic/head and neck medical oncology at the University of Texas M.D. Anderson Cancer Center, is scheduled to present the finding Saturday at the American Society of Clinical Oncology annual meeting, in Chicago.


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Monday, June 7, 2010

Studies show combo chemotherapy, new drug prolonged lives of some with advanced diseaseBy Amanda Gardner
HealthDay Reporter


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